BDBM50543439 CHEMBL4642977

SMILES COC[C@@H]1NC(=O)[C@H](C)N(Cc2ccc(Cl)cc2Oc2ccc(nc2)-c2cnc(CN(C)C)n2C)C(=O)C[C@@H](CC(F)(F)F)C(=O)N2CCC[C@@](Cc3ccc(Cl)cc3)(C2)N(C)C1=O

InChI Key InChIKey=OGQMNAXCCVMAIA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50543439   

TargetProprotein convertase subtilisin/kexin type 9(Human)
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM50543439(CHEMBL4642977)
Affinity DataIC50: 0.152nMAssay Description:Inhibition of human PCSK9 by Alexa Fluor 647 staining based TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed