BDBM50543814 CHEMBL4644497

SMILES Cn1nccc1CCOc1cc(F)c(cc1F)S(=O)(=O)Nc1ncns1

InChI Key InChIKey=RUZRQWYTSWEZCR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50543814   

TargetSodium channel protein type 1 subunit alpha/subunit beta-1/subunit beta-2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50543814(CHEMBL4644497)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human NaV1.1/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium channel subunit beta-2(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50543814(CHEMBL4644497)
Affinity DataIC50:  3.53E+4nMAssay Description:Inhibition of mouse NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium channel subunit beta-2(Homo sapiens)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50543814(CHEMBL4644497)
Affinity DataIC50:  800nMAssay Description:Inhibition of human NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha/subunit beta-1/subunit beta-2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50543814(CHEMBL4644497)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human NaV1.5/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed