BDBM50543905 CHEMBL4637996

SMILES Cc1ccc(cc1)-c1ncnc(Nc2ccc3C(=N)NCc3c2Cl)c1O

InChI Key InChIKey=SDDLULXLIPJVDU-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50543905   

TargetCoagulation factor IX(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50543905(CHEMBL4637996)
Affinity DataIC50:  34nMAssay Description:Inhibition of activated factor IX (unknown origin) using CH3SO2-D-CHG-Gly-Arg-pNA:AcOH as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50543905(CHEMBL4637996)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of activated factor X (unknown origin) using CH3O-CO-D-CHG-Gly-Arg-pNA-AcOH as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50543905(CHEMBL4637996)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of recombinant human activated factor VII using H-D-Lle-Pro-Arg-pNA as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50543905(CHEMBL4637996)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50543905(CHEMBL4637996)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50543905(CHEMBL4637996)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50543905(CHEMBL4637996)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human activated factor XI using pyroGlu-Pro-Arg-pNA as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed