BDBM50543913 CHEMBL4647759

SMILES NC(=N)c1ccc2[nH]c(nc2c1)-c1ncnc(-c2ccccc2)c1O

InChI Key InChIKey=SUHDNPFGNXJFEB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50543913   

TargetCoagulation factor IX(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50543913(CHEMBL4647759)
Affinity DataIC50: 480nMAssay Description:Inhibition of activated factor IX (unknown origin) using CH3SO2-D-CHG-Gly-Arg-pNA:AcOH as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50543913(CHEMBL4647759)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of recombinant human activated factor VII using H-D-Lle-Pro-Arg-pNA as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50543913(CHEMBL4647759)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of human activated factor XI using pyroGlu-Pro-Arg-pNA as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50543913(CHEMBL4647759)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of activated factor X (unknown origin) using CH3O-CO-D-CHG-Gly-Arg-pNA-AcOH as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed