BDBM50544028 CHEMBL4641017

SMILES CC(C)c1onc(c1COc1ccc(cc1)-c1nc2ccc(cc2n1C1CCCCC1)C(O)=O)-c1c(Cl)cccc1Cl

InChI Key InChIKey=PHHBYBVJBFUUCM-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50544028   

TargetBile acid receptor(Human)
Hiroshima International University

Curated by ChEMBL
LigandPNGBDBM50544028(CHEMBL4641017)
Affinity DataEC50:  4.20nMAssay Description:Agonist activity at human FXR expressed in human HuH7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
Hiroshima International University

Curated by ChEMBL
LigandPNGBDBM50544028(CHEMBL4641017)
Affinity DataIC50: 1.45E+3nMAssay Description:Antagonist activity at human VDR transfected in HEK293T cells measured after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed