BDBM50544089 CHEMBL4649261
SMILES COc1cc(ccc1Nc1nccc(n1)-c1cn(CCCO)c2ccccc12)N(C)CCN(C)C
InChI Key InChIKey=NXVBLFLXCQUOFT-UHFFFAOYSA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50544089
TargetEpidermal growth factor receptor(Human)
East China University of Science & Technology
Curated by ChEMBL
East China University of Science & Technology
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of EGFR 19D/T790M/C797S mutant (unknown origin) by ELISAMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Human)
East China University of Science & Technology
Curated by ChEMBL
East China University of Science & Technology
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of EGFR Del19/T790M/C797S triple mutant (unknown origin)More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Human)
East China University of Science & Technology
Curated by ChEMBL
East China University of Science & Technology
Curated by ChEMBL
Affinity DataIC50: 157nMAssay Description:Inhibition of EGFR L858R/T790M double mutant (unknown origin)More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Human)
East China University of Science & Technology
Curated by ChEMBL
East China University of Science & Technology
Curated by ChEMBL
Affinity DataIC50: 157nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin) by ELISAMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Human)
East China University of Science & Technology
Curated by ChEMBL
East China University of Science & Technology
Curated by ChEMBL
Affinity DataIC50: 218nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin)More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Human)
East China University of Science & Technology
Curated by ChEMBL
East China University of Science & Technology
Curated by ChEMBL
Affinity DataIC50: 218nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin)More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Human)
East China University of Science & Technology
Curated by ChEMBL
East China University of Science & Technology
Curated by ChEMBL
Affinity DataIC50: 218nMAssay Description:Inhibition of EGFR L858R/T790M/C797S mutant (unknown origin) by ELISAMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Human)
East China University of Science & Technology
Curated by ChEMBL
East China University of Science & Technology
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of wild type EGFR (unknown origin) by ELISAMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Human)
East China University of Science & Technology
Curated by ChEMBL
East China University of Science & Technology
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of wild type EGFR (unknown origin)More data for this Ligand-Target Pair
