BDBM50544090 CHEMBL4647073

SMILES CCC(=O)Nc1cc(Nc2nccc(n2)-c2cn(CCCO)c3ccc(F)cc23)c(OC)cc1F

InChI Key InChIKey=QOLPXWZZCOBIHS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50544090   

TargetEpidermal growth factor receptor(Human)
East China University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50544090(CHEMBL4647073)
Affinity DataIC50: 40nMAssay Description:Inhibition of EGFR 19D/T790M/C797S mutant (unknown origin) by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
East China University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50544090(CHEMBL4647073)
Affinity DataIC50: 142nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin) by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
East China University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50544090(CHEMBL4647073)
Affinity DataIC50: 332nMAssay Description:Inhibition of EGFR L858R/T790M/C797S mutant (unknown origin) by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
East China University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50544090(CHEMBL4647073)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of wild type EGFR (unknown origin) by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed