BDBM50544097 CHEMBL4647548

SMILES C1CC1n1cc(Oc2ccnc(Nc3ccnc(NC4CCOCC4)c3)c2)c(n1)C1CCOCC1

InChI Key InChIKey=WHBKZHOCVCXTPT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50544097   

TargetTGF-beta receptor type-1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50544097(CHEMBL4647548)
Affinity DataIC50: 17nMAssay Description:Inhibition of ALK5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50544097(CHEMBL4647548)
Affinity DataIC50: 133nMAssay Description:Inhibition of ALK5 (unknown origin) expressed in mouse NIH/3T3 cells by cell-based luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed