BDBM50544102 CHEMBL4641072

SMILES CC1(O)CN(C1)c1cc(Nc2cc(Oc3cn(nc3C3CCOCC3)C3CC3)ccn2)ccc1C#N

InChI Key InChIKey=XJOWZMINWBTRJB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50544102   

TargetTGF-beta receptor type-1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50544102(CHEMBL4641072)
Affinity DataIC50: 14nMAssay Description:Inhibition of ALK5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50544102(CHEMBL4641072)
Affinity DataIC50: 86nMAssay Description:Inhibition of ALK5 (unknown origin) expressed in mouse NIH/3T3 cells by cell-based luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed