BDBM50544133 CHEMBL4636148

SMILES CN1CCc2cccc3-c4cc(NC(N)=O)ccc4CC1c23

InChI Key InChIKey=YBSSDSCEOFCFIV-UHFFFAOYSA-N

Data  3 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50544133   

Target5-hydroxytryptamine receptor 7(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50544133(CHEMBL4636148)
Affinity DataKi:  4.5nMAssay Description:Displacement of [3H]-LSD from human 5-HT7A receptor expresssed in stable HEK cell membrane incubated for 90 mins by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50544133(CHEMBL4636148)
Affinity DataKi:  49nMAssay Description:Displacement of [3H]-WAY100635 from human 5-HT1A receptor expresssed in stable CHO cell membrane incubated for 90 mins by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50544133(CHEMBL4636148)
Affinity DataIC50: 125nMAssay Description:Antagonist activity at human recombinant 5-HT7 receptor expressed in CHOK1 Hunter cell preincubated for 30 mins followed by incubation with agonist f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50544133(CHEMBL4636148)
Affinity DataKi:  2.46E+3nMAssay Description:Displacement of [3H]-N-Methylspiperone from dopamine D3 receptor (unknown origin) incubated for 90 mins by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50544133(CHEMBL4636148)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human recombinant 5-HT7 receptor expressed in CHOK1 Hunter cell incubated for 30 to 60 mins by hit-hunter cAMP assay based chemil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed