BDBM50544844 CHEMBL4635691

SMILES CCC[C@@H](C)Oc1nc(N)c2[nH]c(=O)n(CC3CCNCC3)c2n1

InChI Key InChIKey=WWERPRNMMZHZPG-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50544844   

TargetToll-like receptor 7(Human)
University of Montana

Curated by ChEMBL
LigandPNGBDBM50544844(CHEMBL4635691)
Affinity DataEC50:  3.58E+4nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells assessed as induction of NFKappaB activity after 24 hrs by SEAP reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
University of Montana

Curated by ChEMBL
LigandPNGBDBM50544844(CHEMBL4635691)
Affinity DataEC50:  6.19E+5nMAssay Description:Agonist activity at human TLR8 expressed in HEK293 cells assessed as induction of NFKappaB activity after 24 hrs by SEAP reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed