BDBM50545279 CHEMBL4648924

SMILES CC1CCCCN1C\C=C\C(=O)N1CCOc2cc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3cc12

InChI Key InChIKey=WZZFUXVTYMYBAM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50545279   

TargetEpidermal growth factor receptor(Human)
Jiangsu Aosaikang Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50545279(CHEMBL4648924)
Affinity DataIC50: 179nMAssay Description:Inhibition of EGFR in human KB cells assessed as reduction in EGF-stimulated EGFR phosphorylation preincubated for 1 hr followed by EGF stimulation a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed