BDBM50545305 CHEMBL4632448

SMILES Fc1ccc2nc(Nc3cc(ccc3-c3ccsc3)S(=O)(=O)NC3CC3)[nH]c2c1F

InChI Key InChIKey=FAKXKVVWTFSTAN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50545305   

TargetIsocitrate dehydrogenase [NADP], mitochondrial(Human)
Shandong Provincial Hospital Affiliated To Shandong University

Curated by ChEMBL
LigandPNGBDBM50545305(CHEMBL4632448)
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of IDH2 R140Q mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed