BDBM50545410 CHEMBL4635395

SMILES Cc1cccc(Nc2ccccc2COCc2cc3cc(F)ccc3n2S(C)(=O)=O)c1C

InChI Key InChIKey=KQWYTSJIOZXRPI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50545410   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Andhra University

Curated by ChEMBL
LigandPNGBDBM50545410(CHEMBL4635395)
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition of recombinant human PDE4B expressed in baculovirus infected Sf9 cells using [3H] cAMP as substrate after 30 min by scintillation proximit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
LigandPNGBDBM50545410(CHEMBL4635395)
Affinity DataIC50: 5.81E+3nMAssay Description:Inhibition of PDE4 (unknown origin) assessed as inhibition of TNF-alpha releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed