BDBM50545427 CHEMBL4637032

SMILES CN1CCN(CCC(=O)Nc2ccc(cc2)-c2cn3c(nn(-c4ccccc4)c3=O)c(N)n2)CC1

InChI Key InChIKey=XYSRFXJWVVBKGT-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50545427   

TargetAdenosine receptor A2a(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50545427(CHEMBL4637032)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]-NECA from human A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50545427(CHEMBL4637032)
Affinity DataKi:  663nMAssay Description:Displacement of [3H]-CCPA from human A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50545427(CHEMBL4637032)
Affinity DataKi:  3.10E+3nMAssay Description:Displacement of [3H]-HEMADO from human A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50545427(CHEMBL4637032)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity against human A2B adenosine receptor expressed in CHO cells assessed as inhibition of NECA-induced adenylyl cylase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed