BDBM50545567 CHEMBL4649638

SMILES FC(F)(F)c1ccc([C@H]2CCOc3cc(ccc23)S(=O)(=O)Nc2nccs2)c(c1)N1CCNCC1

InChI Key InChIKey=ZRUOUOQFNMKUDU-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50545567   

TargetSodium channel protein type 9 subunit alpha(Human)
Lupin

Curated by ChEMBL

LigandBDBM50545567(CHEMBL4649638)Copy SMILESCopy InChI

Affinity DataIC50: 0.800nMAssay Description:Inhibition of Nav1.7 (unknown origin) expressed in HEK293 cells assessed as reduction in veratridine-induced depolarization preincubated for 15 to 20...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/14/2021
Entry Details Article
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TargetSodium channel protein type 5 subunit alpha(Human)
Lupin

Curated by ChEMBL

LigandBDBM50545567(CHEMBL4649638)Copy SMILESCopy InChI

Affinity DataIC50: 4.09E+3nMAssay Description:Inhibition of Nav1.5 (unknown origin) expressed in HEK293 cells assessed as reduction in veratridine-induced depolarization preincubated for 15 to 20...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/14/2021
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL