BDBM50545568 CHEMBL4632456

SMILES CN1CCN(CC1)c1cc(ccc1[C@H]1CCOc2cc(ccc12)S(=O)(=O)Nc1nccs1)C(F)(F)F

InChI Key InChIKey=XOKHNIWKPBYBRC-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50545568   

TargetSodium channel protein type 9 subunit alpha(Human)
Lupin

Curated by ChEMBL

LigandBDBM50545568(CHEMBL4632456)Copy SMILESCopy InChI

Affinity DataIC50: 6.90nMAssay Description:Inhibition of Nav1.7 (unknown origin) expressed in HEK293 cells assessed as reduction in veratridine-induced depolarization preincubated for 15 to 20...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/14/2021
Entry Details Article
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TargetSodium channel protein type 5 subunit alpha(Human)
Lupin

Curated by ChEMBL

LigandBDBM50545568(CHEMBL4632456)Copy SMILESCopy InChI

Affinity DataIC50: 983nMAssay Description:Inhibition of Nav1.5 (unknown origin) expressed in HEK293 cells assessed as reduction in veratridine-induced depolarization preincubated for 15 to 20...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/14/2021
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL