BDBM50545664 CHEMBL4636159

SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@]5(Cc1cc(cnc21)-c1ccc(OC)cc1)OCCCc1ccccc1)ccc3O

InChI Key

Data  3 KI  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50545664   

TargetKappa-type opioid receptor(Human)
University of Alabama At Birmingham

Curated by ChEMBL
LigandPNGBDBM50545664(CHEMBL4636159)
Affinity DataEC50:  2nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Alabama At Birmingham

Curated by ChEMBL
LigandPNGBDBM50545664(CHEMBL4636159)
Affinity DataIC50: 22nMAssay Description:Antagonist activity at human delta opioid receptor expressed in CHO cell membranes assessed as reduction in SNC80-induced [35S]GTPgammaS binding prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Alabama At Birmingham

Curated by ChEMBL
LigandPNGBDBM50545664(CHEMBL4636159)
Affinity DataEC50:  24nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cell membranes incubated for 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Alabama At Birmingham

Curated by ChEMBL
LigandPNGBDBM50545664(CHEMBL4636159)
Affinity DataKi:  31nMAssay Description:Displacement of [3H]-diprenorphine from human delta opioid receptor expressed in CHO cell membranes incubated for 1 hr by competition radioligand bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Alabama At Birmingham

Curated by ChEMBL
LigandPNGBDBM50545664(CHEMBL4636159)
Affinity DataKi:  140nMAssay Description:Displacement of [3H]-diprenorphine from human kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by competition radioligand bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Alabama At Birmingham

Curated by ChEMBL
LigandPNGBDBM50545664(CHEMBL4636159)
Affinity DataKi:  148nMAssay Description:Displacement of [3H]-diprenorphine from human mu opioid receptor expressed in CHO cell membranes incubated for 1 hr by competition radioligand bindin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed