BDBM50546416 CHEMBL4778087

SMILES Cc1ccccc1N1CCN(CC1)C(=O)N1C[C@H](Cc2cc(Cl)ccc12)C(=O)N1CCCC1

InChI Key InChIKey=WHFQNYFSMHRFHY-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50546416   

TargetVasopressin V1a receptor(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50546416(CHEMBL4778087)
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]AVP from human V1a receptor expressed in 1132N1 cells assessed as dissociation constant by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50546416(CHEMBL4778087)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human V1a receptor expressed in human 1321N1 cells assessed as decrease in Arg8-vasopressin-stimulated calcium flux by fluorometric cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed