BDBM50546425 CHEMBL4756354

SMILES COC(=O)CC1Cc2cc(Cl)ccc2-n2c1nnc2[C@H]1CC[C@@H](CC1)Oc1ccccn1

InChI Key InChIKey=CGKQLPQCUUZNKB-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50546425   

TargetVasopressin V1a receptor(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50546425(CHEMBL4756354)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]AVP from human V1a receptor expressed in 1132N1 cells assessed as dissociation constant by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50546425(CHEMBL4756354)
Affinity DataIC50: 220nMAssay Description:Inhibition of human V1a receptor expressed in human 1321N1 cells assessed as decrease in Arg8-vasopressin-stimulated calcium flux by fluorometric cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed