BDBM50547451 CHEMBL4778164

SMILES CC[S+]([O-])Cc1csc(\C=C\S(=O)(=O)NC(=O)Nc2c3CCCc3cc3CCCc23)n1

InChI Key InChIKey=TYEXOGDFILZQCS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50547451   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50547451(CHEMBL4778164)
Affinity DataIC50: 243nMAssay Description:Inhibition of NLRP3 in human THP1 cells assessed as inhibition of IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed