BDBM50547762 CHEMBL4799257
SMILES FC(F)(F)c1ccc(cc1)C(=O)N1CCC[C@@H](C1)c1ccnc2ncnn12
InChI Key InChIKey=JKSXJOKIOBKRPN-ZDUSSCGKSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50547762
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Janssen Pharmaceutica N. V.
Curated by ChEMBL
Janssen Pharmaceutica N. V.
Curated by ChEMBL
Affinity DataIC50: 324nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rat)
Janssen Pharmaceutica N. V.
Curated by ChEMBL
Janssen Pharmaceutica N. V.
Curated by ChEMBL
Affinity DataIC50: 3.02E+3nMAssay Description:Inhibition of 6xHis-tagged rat recombinant PDE10A2 expressed in Sf9 cells in presence of [3H]-cAMP and cAMP incubated for 60 mins by scintillation co...More data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Janssen Pharmaceutica N. V.
Curated by ChEMBL
Janssen Pharmaceutica N. V.
Curated by ChEMBL
Affinity DataIC50: 436nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE3A expressed in Sf9 cells in presence of [3H]-cAMP and cAMP incubated for 60 mins by scintillation co...More data for this Ligand-Target Pair