BDBM50547791 CHEMBL4798804

SMILES CNC(=O)c1ccnc(c1)N1CCC(C)C(C1)c1cc(nc2ncnn12)C(F)F

InChI Key InChIKey=IVOPGUDJAXXMCV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50547791   

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL
LigandPNGBDBM50547791(CHEMBL4798804)
Affinity DataIC50:  9.12E+3nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE3A expressed in Sf9 cells in presence of [3H]-cAMP and cAMP incubated for 60 mins by scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL
LigandPNGBDBM50547791(CHEMBL4798804)
Affinity DataIC50:  110nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed