BDBM50547870 CHEMBL4798215
SMILES CC(C)n1c2nc(N[C@@H]3CNC[C@@H](F)C3)ncc2nc(-c2ccc(NS(=O)(=O)Cc3ccc(cc3)C#N)c(F)c2)c1=O
InChI Key InChIKey=MDSOQZGJTZIQCG-SFTDATJTSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50547870
TargetSerine/threonine-protein kinase/endoribonuclease IRE1(Human)
Smith, Gambrell & Russell
Curated by ChEMBL
Smith, Gambrell & Russell
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human His-tagged IRE1alpha expressed in Sf9 insect cells preincubated for 1 hr followed by Alexa fluor 647-labeled probe addition and m...More data for this Ligand-Target Pair