BDBM50547949 CHEMBL4743091

SMILES Nc1ccc(cn1)-c1cccc(n1)C(=O)Nc1cc2oc(nc2nc1N1CCCCC1)N1CCOCC1

InChI Key InChIKey=MDMIHIDXCRKPKM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50547949   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50547949(CHEMBL4743091)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged human IRAK4 expressed in baculovirus infected sf9 cells using biotinylated histone H3 as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed