BDBM50548408 CHEMBL4757413

SMILES COc1ccc-2c(CCn3c-2cc(OCc2ncccc2F)nc3=O)c1

InChI Key InChIKey=KHKZSYUBQXTNKR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50548408   

TargetG-protein coupled receptor 84(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50548408(CHEMBL4757413)
Affinity DataIC50: 595nMAssay Description:Antagonist activity at recombinant human GPR84 stably overexpressed in HEK293T cell membranes co-expressing G-alpha assessed as inhibition of DIM-sti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50548408(CHEMBL4757413)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human PDE4A overexpressed in HEK293 cells assessed as reduction in cAMP hydrolysis by HTRF based immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed