BDBM50548592 CHEMBL4786270

SMILES Nc1nc(nn1C(=O)Cc1ccccc1I)-c1ccccn1

InChI Key InChIKey=YVFPJFVEQPRRJJ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50548592   

TargetCoagulation factor XII(Human)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM50548592(CHEMBL4786270)
Affinity DataIC50: 62nMAssay Description:Inhibition of human coagulation factor XIIA using Boc-Gln-Gly-Arg-AMC as fluorogenic substrate measured at 1 min interval for 1 hr by fluorometric as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetProthrombin(Human)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM50548592(CHEMBL4786270)
Affinity DataIC50: 1.82E+3nMAssay Description:Inhibition of human coagulation factor alpha-thrombin using Boc-Val-Pro-Arg-AMC as fluorogenic substrate measured at 1 min interval for 1 hr by fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM50548592(CHEMBL4786270)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human coagulation factor Xa using Boc-Ile-Glu-Gly-Arg-AMC as fluorogenic substrate measured at 1 min interval for 1 hr by fluorometric ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetPlasma kallikrein(Human)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM50548592(CHEMBL4786270)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human kallikrein using Mes-dArg-Pro-Arg-AMC as fluorogenic substrate measured at 1 min interval for 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetPlasminogen(Human)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM50548592(CHEMBL4786270)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human plasmin using Mes-dArg-Phe-Arg-AMC as fluorogenic substrate measured at 1 min interval for 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM50548592(CHEMBL4786270)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human coagulation factor XIA using Mes-dArg-Pro-Arg-AMC as fluorogenic substrate measured at 1 min interval for 1 hr by fluorometric as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed