BDBM50548674 CHEMBL4787850

SMILES N#Cc1ccc(N2CCN(CCCc3cc4c(N)cccc4c(=O)[nH]3)CC2)cc1

InChI Key InChIKey=DQFNQJDEGHPCEJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50548674   

TargetPoly [ADP-ribose] polymerase 1(Human)
Lupin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50548674BDBM50548674(CHEMBL4787850)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of N-terminal GST-tagged human full length PARP1 (2 to 1041 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Lupin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50548674BDBM50548674(CHEMBL4787850)
Affinity DataIC50: 7.20nMAssay Description:Inhibition of N-terminal GST-tagged human PARP2 (2 to 583 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H2A and H2B) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed