BDBM50548678 CHEMBL4777158

SMILES N#Cc1ccc(N2CCN([C@@H]3C=C(c4cc5c(N)cc(F)cc5c(=O)[nH]4)CC3)CC2)cc1

InChI Key InChIKey=PQHSBQMZINJNST-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50548678   

TargetPoly [ADP-ribose] polymerase 1(Human)
Lupin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50548678BDBM50548678(CHEMBL4777158)
Affinity DataIC50: 5nMAssay Description:Inhibition of N-terminal GST-tagged human full length PARP1 (2 to 1041 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Lupin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50548678BDBM50548678(CHEMBL4777158)
Affinity DataIC50: 200nMAssay Description:Inhibition of N-terminal GST-tagged human PARP2 (2 to 583 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H2A and H2B) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed