BDBM50548684 CHEMBL4746309

SMILES N#Cc1ccc(N2CCN([C@H]3C=C(c4cc5ncccc5c(=O)[nH]4)CC3)CC2)nc1

InChI Key InChIKey=OQXRCISZYORQBS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50548684   

TargetPoly [ADP-ribose] polymerase 1(Human)
Lupin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50548684BDBM50548684(CHEMBL4746309)
Affinity DataIC50: 1nMAssay Description:Inhibition of N-terminal GST-tagged human full length PARP1 (2 to 1041 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Lupin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50548684BDBM50548684(CHEMBL4746309)
Affinity DataIC50: 17nMAssay Description:Inhibition of N-terminal GST-tagged human PARP2 (2 to 583 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H2A and H2B) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed