BDBM50548711 CHEMBL4761823

SMILES C1N[C@H](CC=C1)c1cccnc1

InChI Key InChIKey=SOPPBXUYQGUQHE-UHFFFAOYSA-N

Data  1 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50548711   

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50548711(CHEMBL4761823)
Affinity DataKi:  119nMAssay Description:Displacement of 3H-cytisine from Sprague-Dawley rat brain alpha4beta2 nAChR by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50548711(CHEMBL4761823)
Affinity DataEC50:  740nMAssay Description:Agonist activity at human brain alpha4beta2 nAChR expressed in Xenopus laevis oocytes assessed as peak responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50548711(CHEMBL4761823)
Affinity DataEC50:  5.18E+4nMAssay Description:Agonist activity at human brain alpha7 nAChR expressed in Xenopus laevis oocytes assessed as peak responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed