BDBM50549191 CHEMBL4779641

SMILES CC(C)Cc1nc2n(C)c3ccccc3c(=O)c2c(=O)n1-c1ccc(Cl)cc1

InChI Key InChIKey=IWIKPPNCDBOEMO-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50549191   

TargetD(1B) dopamine receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50549191(CHEMBL4779641)
Affinity DataEC50:  56nMAssay Description:Positive allosteric modulator activity at human dopamine D5 receptor expressed in CHO-K1 cells assessed as potentiation of dopamine-induced beta-arre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50549191(CHEMBL4779641)
Affinity DataEC50:  150nMAssay Description:Positive allosteric modulator activity at human dopamine D1 receptor expressed in HEK293 cells assessed as potentiation of dopamine-induced cAMP accu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50549191(CHEMBL4779641)
Affinity DataEC50:  380nMAssay Description:Positive allosteric modulator activity at human dopamine D1 receptor expressed in CHO-K1 cells assessed as potentiation of dopamine-induced beta-arre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed