BDBM50549543 CHEMBL4746699

SMILES Fc1ccc2nccc(C3CCN(CC3)C(=O)C(=O)Nc3ccc(Cl)cc3)c2c1

InChI Key InChIKey=BBNKZBRNGRLKCM-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50549543   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Phenex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50549543(CHEMBL4746699)
Affinity DataIC50: 15nMAssay Description:Inhibition of IDO1 in human SKOV3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Phenex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50549543(CHEMBL4746699)
Affinity DataIC50: 15nMAssay Description:Inhibition of IDO1 in human SKOV3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Phenex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50549543(CHEMBL4746699)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of IDO1 in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Phenex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50549543(CHEMBL4746699)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of IDO1 in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetCytochrome P450 2C8(Human)
Phenex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50549543(CHEMBL4746699)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of CYP2C8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Phenex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50549543(CHEMBL4746699)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Phenex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50549543(CHEMBL4746699)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of TDO in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Phenex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50549543(CHEMBL4746699)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed