BDBM50549706 CHEMBL4744083

SMILES Cc1ccc(cc1)S(=O)(=O)Nc1ccc(nn1)-c1ccccc1N1CCCCC1

InChI Key InChIKey=HTWCHXFUFLELFB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50549706   

TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50549706(CHEMBL4744083)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of human liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50549706(CHEMBL4744083)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of human liver mitochondrial KMO assessed as reduction in 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Mus musculus)
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50549706(CHEMBL4744083)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of mouse liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed