BDBM50549747 CHEMBL4749193

SMILES CCN1c2sc(C)nc2C(=O)N(C)c2cnc(Nc3ccc(cc3OC)N3CCC(CC3)N3CCN(C)CC3)nc12

InChI Key InChIKey=GBCMBDNJISPETG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50549747   

TargetFocal adhesion kinase 1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50549747(CHEMBL4749193 | US12365696, Compound 159)
Affinity DataIC50: 22.9nMAssay Description:Using a bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514), 100 nL of 100× test compound in 100% DMSO was added. Followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50549747(CHEMBL4749193 | US12365696, Compound 159)
Affinity DataIC50: 23nMAssay Description:Inhibition of Focal adhesion kinase (unknown origin) using Tyr 07 peptide substrate incubated for 60 mins at room temperature followed by 60 mins dev...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed