BDBM50550066 CHEMBL4798954

SMILES Oc1cccc([C@@]23CCC[C@H]([C@H]2O)N(CCc2ccccc2)CC3)c1

InChI Key InChIKey=YJDWRJHIVSZYJV-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50550066   

TargetMu-type opioid receptor(Human)
National Institute On Drug Abuse

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550066BDBM50550066(CHEMBL4798954)
Affinity DataEC50:  0.0170nMAssay Description:Agonist activity at human MOR expressed in CHOK1 cells assessed as inhibition of forskolin-stimulated cAMP accumulation incubated for 30 mins by lumi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
National Institute On Drug Abuse

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550066BDBM50550066(CHEMBL4798954)
Affinity DataEC50:  2.60nMAssay Description:Agonist activity at human DOR expressed in CHOK1 cells assessed as inhibition of forskolin-stimulated cAMP accumulation incubated for 30 mins by lumi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Institute On Drug Abuse

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550066BDBM50550066(CHEMBL4798954)
Affinity DataEC50:  6.10nMAssay Description:Activity at human MOR expressed in CHOK1 cells co-expressing beta-arrestin2 EFC assessed as beta-arrestin2 EFC recruitment measured after 90 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
National Institute On Drug Abuse

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550066BDBM50550066(CHEMBL4798954)
Affinity DataEC50:  323nMAssay Description:Agonist activity at human KOR expressed in CHOK1 cells assessed as inhibition of forskolin-stimulated cAMP accumulation incubated for 30 mins by lumi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed