BDBM50550069 CHEMBL4748910

SMILES COC(=O)CC[C@@H]1[C@@H]2CCC[C@@]1(c1cccc(O)c1)CCN2CCc1ccccc1

InChI Key InChIKey=NIGWAKMPTZHINX-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50550069   

TargetKappa-type opioid receptor(Human)
National Institute On Drug Abuse

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550069BDBM50550069(CHEMBL4748910)
Affinity DataEC50:  323nMAssay Description:Agonist activity at human KOR expressed in CHOK1 cells assessed as inhibition of forskolin-stimulated cAMP accumulation incubated for 30 mins by lumi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Institute On Drug Abuse

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550069BDBM50550069(CHEMBL4748910)
Affinity DataEC50:  854nMAssay Description:Agonist activity at human MOR expressed in CHOK1 cells assessed as inhibition of forskolin-stimulated cAMP accumulation incubated for 30 mins by lumi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
National Institute On Drug Abuse

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550069BDBM50550069(CHEMBL4748910)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human DOR expressed in CHOK1 cells assessed as inhibition of forskolin-stimulated cAMP accumulation incubated for 30 mins by lumi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Institute On Drug Abuse

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550069BDBM50550069(CHEMBL4748910)
Affinity DataEC50: >2.50E+4nMAssay Description:Activity at human MOR expressed in CHOK1 cells co-expressing beta-arrestin2 EFC assessed as beta-arrestin2 EFC recruitment measured after 90 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed