BDBM50550071 CHEMBL4747769

SMILES [H][C@@]12CCC[C@@](CCN1CCc1ccccc1)([C@H]2CCC(=O)OCC)c1cccc(O)c1

InChI Key

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50550071   

TargetMu-type opioid receptor(Human)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50550071(CHEMBL4747769)
Affinity DataEC50:  0.240nMAssay Description:Agonist activity at human MOR expressed in CHOK1 cells assessed as inhibition of forskolin-stimulated cAMP accumulation incubated for 30 mins by lumi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50550071(CHEMBL4747769)
Affinity DataEC50:  12nMAssay Description:Activity at human MOR expressed in CHOK1 cells co-expressing beta-arrestin2 EFC assessed as beta-arrestin2 EFC recruitment measured after 90 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50550071(CHEMBL4747769)
Affinity DataEC50:  35nMAssay Description:Agonist activity at human KOR expressed in CHOK1 cells assessed as inhibition of forskolin-stimulated cAMP accumulation incubated for 30 mins by lumi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50550071(CHEMBL4747769)
Affinity DataEC50:  49nMAssay Description:Agonist activity at human DOR expressed in CHOK1 cells assessed as inhibition of forskolin-stimulated cAMP accumulation incubated for 30 mins by lumi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50550071(CHEMBL4747769)
Affinity DataEC50: >2.50E+4nMAssay Description:Activity at human MOR expressed in U2OS cells co-expressing beta-arrestin2 EFC assessed as beta-arrestin2 EFC recruitment by Tango assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed