BDBM50550211 CHEMBL4741076

SMILES Cn1nc-2c(CCc3cc(CN4CC(C4)C(O)=O)ccc-23)c1-c1noc(c1C(F)(F)F)-c1ccccc1

InChI Key InChIKey=FQYNKXFGKCLGCP-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50550211   

TargetSphingosine 1-phosphate receptor 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50550211(CHEMBL4741076)
Affinity DataEC50:  380nMAssay Description:Agonist activity at human S1P1 expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgamma-S binding measured after 45 mins by liquid s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50550211(CHEMBL4741076)
Affinity DataEC50: >6.30E+4nMAssay Description:Agonist activity at human S1P3 expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgamma-S binding measured after 45 mins by liquid s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed