BDBM50550413 CHEMBL4764584

SMILES Cc1cccc(COc2nc(ccc2C(=O)NC2CCCCC2)N2CCC[C@@H](CC(O)=O)C2)c1

InChI Key InChIKey=NBASOQAMMYVWAS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50550413   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50550413(CHEMBL4764584)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed