BDBM50550796 CHEMBL4779428

SMILES CC(C)CN(C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)Cc1cc(=O)oc2cc(O)ccc12)S(=O)(=O)c1ccc(cc1)[N+]([O-])=O

InChI Key InChIKey=LKHULGUQAALLGL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50550796   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50550796(CHEMBL4779428)
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant HIV1 protease measured assessed as hydrolysis of fluorogenic substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50550796(CHEMBL4779428)
Affinity DataIC50: 367nMAssay Description:Inhibition of HIV-1BH10 reverse transcriptase expressed in Escherichia coli assessed as polymerization by real time FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed