BDBM50550804 CHEMBL4759897

SMILES CC(C)CN(C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)c1cc2ccccc2oc1=O)S(=O)(=O)c1ccc(N)cc1

InChI Key InChIKey=JLWXEFNEFHBDLL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50550804   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50550804(CHEMBL4759897)
Affinity DataIC50: 75nMAssay Description:Inhibition of HIV-1BH10 reverse transcriptase expressed in Escherichia coli assessed as polymerization by real time FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50550804(CHEMBL4759897)
Affinity DataIC50: 156nMAssay Description:Inhibition of recombinant HIV1 protease measured assessed as hydrolysis of fluorogenic substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed