BDBM50551186 CHEMBL4785934

SMILES NS(=O)(=O)c1ccc(cc1)-n1nc(cc1-c1cc2ccccc2s1)C(O)=O

InChI Key InChIKey=WQYDAOYIYVNTGB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50551186   

TargetProstaglandin G/H synthase 2(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50551186(CHEMBL4785934)
Affinity DataIC50: 10nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha formation using arachidonic acid as substrate preincubated for 10 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50551186(CHEMBL4785934)
Affinity DataIC50: 1.78E+3nMAssay Description:Inhibition of 5-LOX (unknown origin) using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition and measured after 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50551186(CHEMBL4785934)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of human COX1 assessed as reduction in PGF2alpha formation using arachidonic acid as substrate preincubated for 10 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed