BDBM50551248 CHEMBL4760138

SMILES O=c1c2c(Cl)cccc2nc([C@@H]2CC3(CC3)CN2c2ncnc3[nH]cnc23)n1-c1ccccc1

InChI Key InChIKey=JMCOBLCEJSXBNG-UHFFFAOYSA-N

Data  4 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50551248   

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Anhui University of Chinese Medicine

Curated by ChEMBL

LigandBDBM50551248(CHEMBL4760138)Copy SMILESCopy InChI

Affinity DataIC50: 13nMAssay Description:Inhibition of human full-length recombinant His-tagged PI3K p110delta/p85alpha expressed in baculovirus expression system using PIP2 as substrate mea...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/23/2022
Entry Details Article
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Anhui University of Chinese Medicine

Curated by ChEMBL

LigandBDBM50551248(CHEMBL4760138)Copy SMILESCopy InChI

Affinity DataIC50: 113nMAssay Description:Inhibition of recombinant human full-length His-tagged p110gamma expressed in baculovirus expression system using PIP2 as substrate measured after 2 ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/23/2022
Entry Details Article
Copy BDB DOIPubMed
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TargetPhosphatidylinositol 3-kinase regulatory subunit beta/4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Anhui University of Chinese Medicine

Curated by ChEMBL

LigandBDBM50551248(CHEMBL4760138)Copy SMILESCopy InChI

Affinity DataIC50: 2.64E+3nMAssay Description:Inhibition of human full-length recombinant His-tagged PI3K p110beta/p85beta expressed in baculovirus expression system using PIP2 as substrate measu...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/23/2022
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Anhui University of Chinese Medicine

Curated by ChEMBL

LigandBDBM50551248(CHEMBL4760138)Copy SMILESCopy InChI

Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human full-length recombinant N-terminal His-tagged PI3K p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as su...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/23/2022
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL