BDBM50551366 CHEMBL4748169

SMILES COc1cc2CCN(CCc3ccc(cc3)-n3cc(nn3)-c3ccc(C(=O)C(C)C)c(NC(=O)c4ccc5ccccc5n4)c3)Cc2cc1OC

InChI Key InChIKey=CRDPDHTUSFHKGC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50551366   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551366(CHEMBL4748169)
Affinity DataIC50: 295nMAssay Description:Inhibition of ABCG2 in topotecan-cultured human MCF7 cells using Hoechst 33342 as substrate measured after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed