BDBM50552136 CHEMBL4795753

SMILES C(c1ccccc1)n1c(Sc2ncnc3c4cccnc4sc23)nnc1-c1ccncc1

InChI Key InChIKey=CBBXTGWSGPEJEE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50552136   

TargetToll-like receptor 5(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50552136(CHEMBL4795753)
Affinity DataIC50: 850nMAssay Description:Inhibition of Flagellin-BS binding to human TLR5 expressed in HEK293 cells harboring SEAP reporter gene preincubated for 24 hrs followed by compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetToll-like receptor 5(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50552136(CHEMBL4795753)
Affinity DataIC50: 850nMAssay Description:Antagonist activity at TLR5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed