BDBM50552408 CHEMBL4750971

SMILES Cc1ncccc1C(=O)N([C@@H](C(N)=O)c1ccccc1)[C@@H]1CCc2c1cc(Cl)cc2F

InChI Key InChIKey=LKDFJGBMTHRPTF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50552408   

LigandPNGBDBM50552408(CHEMBL4750971)
Affinity DataIC50: 80nMAssay Description:Antagonist activity at rat TRPM8 transfected in HEK293T cells assessed as reduction in menthol-induced calcium influx measured after 60 mins by Fluo-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50552408(CHEMBL4750971)
Affinity DataIC50: 210nMAssay Description:Antagonist activity at human TRPM8 transfected in HEK293T cells assessed as reduction in menthol-induced calcium influx measured after 60 mins by Flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50552408(CHEMBL4750971)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human TRPV4 transfected in HEK293T cells assessed as reduction in RN1747-induced calcium influx measured after 60 mins by Fura-2 AM dye...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50552408(CHEMBL4750971)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human TRPV1 transfected in HEK293T cells assessed as reduction in capsaicin-induced calcium influx measured after 60 mins by Fluo-4 AM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50552408(CHEMBL4750971)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human TRPA1 transfected in HEK293T cells assessed as reduction in AITC-induced calcium influx measured after 60 mins by Fluo-4 AM dye b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed