BDBM50552469 CHEMBL4792741

SMILES CNC(=O)c1sc(nc1OCC1CCN(Cc2ccc(Br)cc2)CC1)-c1ccnc(NC(=O)C2CC2)c1

InChI Key InChIKey=NANMKYQQTXRMJO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50552469   

TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50552469(CHEMBL4792741)
Affinity DataIC50:  26nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged GSK3beta H350L mutant expressed in baculovirus infected Sf21 cells using prephosphorylated pol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50552469(CHEMBL4792741)
Affinity DataIC50:  6.80E+4nMAssay Description:Inhibition of human BChE using butyrylthiocholineiodide as substrate incubated for 10 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50552469(CHEMBL4792741)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human recombinant AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate incubated for 10 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed