BDBM50552747 CHEMBL4795415::US20240067660, Compound 36
SMILES C[C@H]1C\C=C(F)\C(CO)(CO)N2CC[C@H]2CN2C[C@@]3(CCCc4cc(Cl)ccc34)COc3ccc(cc23)C(=O)NS(=O)(=O)[C@@H]1C
InChI Key InChIKey=YFNDQLGDXMYDNP-UYOXWRSBSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50552747
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Janssen Pharmaceutica NV
US Patent
Janssen Pharmaceutica NV
US Patent
Affinity DataKi: 0.230nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Janssen Pharmaceutica NV
US Patent
Janssen Pharmaceutica NV
US Patent
Affinity DataKi: 0.230nMAssay Description:Inhibition of Terbium-labeled BIM BH3 peptide binding to MCL1 (unknown origin) incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair