BDBM50553263 CHEMBL4790416

SMILES Nc1nc(cc(n1)-c1ccc(OCC#C)cc1)-c1ccc(OCCN2CCOCC2)cc1

InChI Key InChIKey=SZNDVDHYJXHIKM-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50553263   

TargetAmine oxidase [flavin-containing] A(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50553263(CHEMBL4790416)
Affinity DataIC50: 18nMAssay Description:Inhibition of human MAO-A using p-tyramine as substrate preincubated for 15 mins followed by substrate addition and measured after 30 mins by Ample r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50553263(CHEMBL4790416)
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human AChE using Amplex red, acetylthiocholine as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50553263(CHEMBL4790416)
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human AChE using acetylcholine as substrate preincubated for 15 mins followed by substrate addition and measured after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Indian Institute of Technology (Banaras Hindu University)

Curated by ChEMBL
LigandPNGBDBM50553263(CHEMBL4790416)
Affinity DataIC50: 304nMAssay Description:Inhibition of recombinant Electric eel AChE incubated for 15 mins by amplex red reagent based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCholinesterase(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50553263(CHEMBL4790416)
Affinity DataIC50: 660nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate preincubated for 30 mins followed by substrate addition and measured after 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCholinesterase(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50553263(CHEMBL4790416)
Affinity DataIC50: 666nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate preincubated for 30 mins followed by substrate addition and measured after 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
Indian Institute of Technology (Banaras Hindu University)

Curated by ChEMBL
LigandPNGBDBM50553263(CHEMBL4790416)
Affinity DataIC50: 666nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate incubated for 30 mins followed by substrate addition and measured for 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50553263(CHEMBL4790416)
Affinity DataIC50: 9.91E+3nMAssay Description:Inhibition of recombinant human MAO-B using p-tyramine as substrate preincubated for 15 mins followed by substrate addition and measured after 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50553263(CHEMBL4790416)
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibition of recombinant human MAO-A using p-tyramine as substrate preincubated for 15 mins followed by substrate addition and measured after 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed